Sulindac sulfide
CAT:
804-HY-B1786-03
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Sulindac sulfide
- CAS Number: 49627-27-2
- UNSPSC Description: Sulindac sulfide is a noncompetitive γ-secretase inhibitor, with an IC50 of 20.2 μM for γ42-secretase activity.
- Target Antigen: Drug Metabolite; γ-secretase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease;Neuronal Signaling;Stem Cell/Wnt
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/Sulindac_sulfide.html
- Purity: 99.07
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(O)CC(C1=C/2C=CC(F)=C1)=C(C)C2=C\C3=CC=C(SC)C=C3
- Molecular Weight: 340.41
- References & Citations: [1]Takahashi Y, et al. Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation. J Biol Chem. 2003 May 16;278(20):18664-70.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported