Hormone sensitive lipase / HSL Recombinant Rabbit Monoclonal Antibody [PSH07-22]
CAT:
992-HA722810
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
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Hormone sensitive lipase / HSL Recombinant Rabbit Monoclonal Antibody [PSH07-22]
- Description: The main function of hormone-sensitive lipase is to mobilize stored fats. HSL functions to hydrolyze either a fatty acid from a triacylglycerol molecule, freeing a fatty acid and diglyceride, or a fatty acid from a diacylglycerol molecule, freeing a fatty acid and monoglyceride. This process allows energy metabolism in mammals. Although HSL is able to catalyze hydrolysis of triglycerides and diglycerides, another enzyme found in adipose tissue, adipose triglyceride lipase (ATGL), has a higher affinity for triglycerides than HSL, and ATGL predominantly acts as the enzyme for triglyceride-specific hydrolysis in the adipocyte. Hormone-sensitive lipase, which has 11-fold greater affinity for diglycerides than triglycerides, predominantly cleaves these diglycerides, forming 2-monoglyceride and a free fatty acid.
- Alternative Name: Hormone sensitive lipase antibody Hormone sensitive lipase testicular isoform antibody Hormone-sensitive lipase antibody HSL antibody LHS antibody Lipase hormone sensitive antibody LIPE antibody LIPS_HUMAN antibody
- Abbreviation: LIPE
- Swiss Prot: Q05469 Human, P54310 Mouse, P15304 Rat
- Cellular Locus: Cell membrane, Membrane, caveola, Cytoplasm, cytosol, Lipid droplet.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide within human HSL aa 931-980.
- Isotype: IgG
- Clone: PSH07-22
- Conjugation: Non-conjugated
- Type: Recombinant Rabbit monoclonal Antibody
- Applications: WB, IHC-P, IP
- Positive Control: Jurkat cell lysate, SH-SY5Y cell lysate, Mouse brown adipose tissue lysate, Rat brown adipose tissue lysate, human breast tissue, mouse breast tissue, rat breast tissue.
- Concentration: 1 mg/mL
- Dilution: WB: 1:1,000 ;IHC-P: 1:30,000 ;IP: 1-2μg/sample
- Purity: Protein A affinity purified.
- Form: Liquid
- Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
- Molecular Weight: Predicted band size: 117 kDa
- Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
- Recombinant Antibody: Yes