Adipose Triglyceride Lipase Rabbit Polyclonal Antibody

Adipose Triglyceride Lipase Rabbit Polyclonal Antibody

• Description: This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone. Also has acylglycerol transacylase activity. Acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade. Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
• Alternative Name: 1110001C14Rik antibody Adipose triglyceride lipase antibody ATGL antibody ATGL DESNUTRIN antibody Calcium independent phospholipase A2 antibody Calcium-independent phospholipase A2 antibody Desnutrin antibody EC 3.1.1.3 antibody FP17548 antibody IPLA2 zeta antibody IPLA2-zeta antibody Mutant patatin like phospholipase domain containing 2 antibody Patatin like phospholipase domain containing 2 antibody PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING PROTEIN 2 antibody Patatin-like phospholipase domain-containing protein 2 antibody PEDF R antibody PHOSPHOLIPASE A2 CALCIUM INDEPENDENT ZETA antibody Pigment epithelium derived factor antibody Pigment epithelium-derived factor antibody plpl antibody plpl2 antibody PLPL2_HUMAN antibody Pnpla2 antibody Transport secretion protein 2 antibody Transport secretion protein 2.2 antibody Transport-secretion protein 2 antibody Triglyceride hydrolase antibody TTS 2.2 antibody TTS2 antibody TTS2.2 antibody ZETA antibody
• Abbreviation: PNPLA2
• Swiss Prot: Q96AD5 Human
• Cellular Locus: Cell membrane, Lipid droplet.
• Host: Rabbit
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human Adipose Triglyceride Lipase aa 450-504 / 504 (Lumenal).
• Isotype: IgG
• Conjugation: Non-conjugated
• Type: Rabbit polyclonal Antibody
• Applications: WB, IHC-P
• Positive Control: 293 cell lysate, HepG2 cell lysate, A431 cell lysate, human pancreas tissue.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:100-1:500
• Purity: Immunogen affinity purified.
• Form: Liquid
• Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: 55 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: No