DiABZI-4

CAT: 0804-HY-168034-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-168034-01Size:5 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
DiABZI-4 is an oral active STING agonist with broad-spectrum antiviral activity. diABZI-4 induces the production of pro-inflammatory cytokines and lymphocyte activation by activating STING, thereby inhibiting the replication of influenza A virus (IAV), SARS-CoV-2, and human rhinovirus (HRV), with an EC50 range of 11.8-199 nM[1][2].
CAS Number
[2138299-65-5]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/diabzi-4.html
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CC(OC)=C3N2C/C=C/CN4C5=C(OCCCN(C)C)C=C(C(N)=O)C=C5N=C4NC(C6=CC(C)=NN6CC)=O.Cl
Molecular Formula
C40H50ClN13O6
Molecular Weight
844.36
References & Citations
[1]Broeckel R, et al. STING Agonist Induced Innate Immune Responses Drive Anti-Respiratory Virus Activity In Vitro with Limited Antiviral Efficacy In Vivo. ACS Infect Dis. 2024 Sep 13;10 (9) :3392-3407.|[2]Humphries F, et al. A diamidobenzimidazole STING agonist protects against SARS-CoV-2 infection. Sci Immunol. 2021 May 18;6 (59) :eabi9002.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-176541DiABZI-Mal
HY-175168DiABZI-a1
HY-175167DiABZI-i
HY-137320-01DiABZI-C2-NH2
HY-162874-01DiABZI-V/C-DBCO
HY-164278-01DiABZI-V/C-Mal
HY-112921A-01DiABZI STING agonist-1
HY-112921-01DiABZI STING agonist-1 (tautomerism)
HY-112921B-01DiABZI STING agonist-1 (trihydrochloride)
HY-1775165-Diazo-4-oxonorvaline

Alternative Products

CatalogName
MF-0110280-01DiABZI-4
tlrl-diabzi-2diABZI
MF-0118543-01DiABZI-a1
MF-0118018-01DiABZI-Mal
MF-0118816-01DiABZI-i
BA6267-1diABZI-C2-NH2
MBS3846114-01diABZI STING agonist-1
MF-0100551-01DiABZI-V/C-Mal
MF-0110136-01DiABZI-V/C-DBCO
C13678-01DiABZI STING agonist (Compound 3)

Popular Products