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DiABZI-i

CAT: 0013-GTR19264089-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264089-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DiABZI-i functions as an orthogonal STING inhibitor, significantly suppressing cGAMP-induced IFNβ in PBMCs with an IC50 of 49 nM. Additionally, diABZI-i activates V155M SAVI constitutive signaling in a STINGV155M THP-1 cell model, demonstrating potent agonistic activity (EC50: 17 nM) . This compound is applicable in researching monogenic autoinflammatory diseases such as SAVI.
Field of Research
Immunology & Inflammation
Storage Conditions
-20°C
Notes
For research use only.

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