Choline (bitartrate) (Standard)

Choline (bitartrate) (Standard)

• CAS Number: 87-67-2
• UNSPSC Description: Choline (bitartrate) (Standard) is the analytical standard of Choline (bitartrate). This product is intended for research and analytical applications. Choline bitartrate is a vitamin-like essential nutrient, can affect diseases such as liver disease, atherosclerosis and neurological disorders[1][2]. Choline bitartrate is a precursor for the neurotransmitter acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism[3].
• Target Antigen: Endogenous Metabolite; mAChR
• Type: Reference Standards
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease;Neuronal Signaling
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/choline-bitartrate-standard.html
• Smiles: OCC[N+](C)(C)C.O=C(O)[C@H](O)[C@@H](O)C([O-])=O
• Molecular Weight: 253.25
• References & Citations: [1]Hollenbeck CB, et al. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012 Jun;12(2):100-13.|[2]Corbin KD, et al. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012 Mar;28(2):159-65.|[3]Shinobu Kuwae, et al. Development of a chemically defined platform fed-batch culture media for monoclonal antibody-producing CHO cell lines with optimized choline content. Cytotechnology. 2018 Jun;70(3):939-948.|[4]Rebecca C Schugar, et al. Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet. PLoS One. 2013 Aug 29;8(8):e74806.
• Shipping Conditions: Room temperature