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GSK-1440115

CAT: 0804-HY-19924Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19924Size:1 Each
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Description
GSK-1440115 is an antagonist of the Urotensin II Receptor with an IC50 value of 82.3 nM[1].
CAS Number
1003878-16-7
UNSPSC
12352005
Target
Urotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/gsk-1440115.html
Smiles
O=C(C1=CC=C(C2=CC=C([C@@H](N(C(CN3C(COC4=CC(Cl)=C(Cl)C=C34)=O)=O)C)CN5CCOCC5)C=C2)C=C1)O
Molecular Formula
C30H29Cl2N3O6
Molecular Weight
598.47
References & Citations
[1]Tae-Ho Kim, et al. A Novel Urotensin II Receptor Antagonist, KR-36996 Inhibits Smooth Muscle Proliferation through ERK/ROS Pathway. Biomol Ther (Seoul) . 2017 May 1;25 (3) :308-314.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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