Products for Research Use Only
RegisterLogin

VU591 hydrochloride

CAT: 0804-HY-108585-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-108585-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride).
CAS Number
1315380-70-1
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/vu591-hydrochloride.html
Purity
99.0
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=[N+](C1=CC=C2N=C(COCC3=NC4=CC=C([N+]([O-])=O)C=C4N3)NC2=C1)[O-].[H]Cl
Molecular Formula
C16H13ClN6O5
Molecular Weight
404.76
References & Citations
[1]Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79 (1) :42-50.|[2]Masayoshi Okada, et al. Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ. PLoS One. 2020 Nov 13;15 (11) :e0233815.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-108585A-01VU591
HY-B0500BAlverine (hydrochloride)
HY-N14912β-Prumycin hydrochloride
HY-N0300A-01Tetrahydropalmatine (hydrochloride)
HY-172541LN6023 (hydrochloride)
HY-172070-01Metaescaline (hydrochloride)
HY-170052-01α-Isopropylaminohexanophenone (hydrochloride)
HY-168824-01Cypenamine (hydrochloride)
HY-161794A-01SP3N (hydrochloride)
HY-157255α-Dimethylaminopentiophenone (hydrochloride)

Alternative Products

CatalogName
BUP12603-01VU591 hydrochloride
A20009-100VU591 hydrochloride 100mg
A20009-50VU591 hydrochloride 50mg
A20009-5VU591 hydrochloride 5mg
A20009-200VU591 hydrochloride 200mg
A20009-25VU591 hydrochloride 25mg
A20009-10VU591 hydrochloride 10mg
A20009-1VU591 hydrochloride 1mg
A20009-10mM-DVU591 hydrochloride 10mM * 1mL in DMSO
T13320L-01VU591

Popular Products