ADAM-17 Substrate

• Description:

  ADAM-17 Substrate is a fluorescent substrate of ADAM[1].

• UNSPSC:

  12352209

• Target:

  Fluorescent Dye; MMP

• Type:

  Peptides

• Related Pathways:

  Metabolic Enzyme/Protease; Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/adam-17-substrate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)[C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@H](CO)NC([C@H](CO)NC([C@H](CCCNC(N)=N)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CC(C)C)NC(C1=CC=CC=C1N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CNC2=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C2

• Molecular Formula:

  C59H92N22O21

• Molecular Weight:

  1445.50

• References & Citations:

  [1]Anna P Carreca, et al. TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1. Sci Rep. 2020 Jul 21;10 (1) :12067.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported