PKCδ substrate

CAT: 0804-HY-P10421Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P10421Size:1 Each
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Description
PKCδ substrate acts as a nuclear transporter of ERK2 and is involved in ERK2 mediated gene activation. PKCδ is involved in the regulation of cell growth, proliferation, cell cycle arrest, and apoptosis by phosphorylating hBVR and other proteins. PKCδ substrate can be used to study the development of diseases, especially cancer biology[1].
CAS Number
[915155-20-3]
UNSPSC
12352209
Target
ERK
Type
Peptides
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pkcδ-substrate.html
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC3=CC=C(C=C3)O)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N
Molecular Formula
C69H108N24O16
Molecular Weight
1529.75
References & Citations
[1]Gibbs P E M, et al. Formation of ternary complex of human biliverdin reductase-protein kinase Cδ-ERK2 protein is essential for ERK2-mediated activation of Elk1 protein, nuclear factor-κB, and inducible nitric-oxidase synthase (iNOS) [J]. Journal of Biological Chemistry, 2012, 287 (2) : 1066-1079.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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