MARK-IN-1

MARK-IN-1

• CAS Number: 1109283-93-3
• UNSPSC Description: MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of <0.25 nM.
• Target Antigen: AMPK
• Type: Reference compound
• Related Pathways: Epigenetics;PI3K/Akt/mTOR
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/MARK-IN-1.html
• Purity: 98.48
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC(C2=C3N=CC(C4=CN(C)N=C4)=CN3N=C2)=C(C)S1)N[C@H]5C(F)(F)CCC[C@H]5N
• Molecular Weight: 471.53
• References & Citations: [1]Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016 Sep 1;26(17):4362-6.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light)
• Clinical Information: No Development Reported