Products for Research Use Only
RegisterLogin

Sodium propionate

CAT: 0804-HY-B1773A-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1773A-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sodium propionate is an orally active short-chain fatty acid. Sodium propionate can be produced by intestinal bacteria from the metabolism of dietary fiber. Sodium propionate increases PPAR-γ, inhibits NF-κB activation, and reduces COX-2 expression and NO production. Sodium propionate also induces Apoptosis and Autophagy. Sodium propionate reduces HSV-1-induced keratitis. Sodium propionate has anticancer effects against glioblastoma. Sodium propionate exhibits neuroprotective, antioxidant, and anti-inflammatory activities. Sodium propionate can be used in the research of spinal cord injury and Alzheimer's disease[1][2][3][4][5][6].
CAS Number
137-40-6
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Bacterial; COX; Endogenous Metabolite; HSV; NF-κB; NO Synthase; PPAR
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sodium-propionate.html
Purity
99.0
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : ≥ 200 mg/mL
Smiles
O=C(CC)O[Na]
Molecular Formula
C3H5NaO2
Molecular Weight
96.06
Precautions
H302, H315, H319, H335
References & Citations
[1]Filippone A, et al. Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling. Cancers (Basel) . 2022 Dec 29;15 (1) :217. |[2]Filippone A, et al. The anti-inflammatory and antioxidant effects of sodium propionate. International journal of molecular sciences, 2020, 21 (8) : 3026.|[3]Filippone A, et al. Protective effect of sodium propionate in Aβ1-42-induced neurotoxicity and spinal cord trauma. Neuropharmacology. 2020 Apr;166:107977.|[4]Park HS, et al. Sodium propionate exerts anticancer effect in mice bearing breast cancer cell xenograft by regulating JAK2/STAT3/ROS/p38 MAPK signaling. Acta Pharmacol Sin. 2021 Aug;42 (8) :1311-1323. |[5]Sumbria D, et al. Supplementing the Diet with Sodium Propionate Suppresses the Severity of Viral Immuno-inflammatory Lesions. J Virol. 2021 Jan 28;95 (4) :e02056-20. |[6]Lang W, et al. Sodium propionate improves cognitive and memory function in mouse models of Alzheimer's disease. Neurosci Lett. 2022 Nov 20;791:136887.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Isoform
COX-2; HSV-1; PPARγ

Chemical Information

Sodium Propionate

Sodium propionate is an organic sodium salt comprising equal numbers of sodium and propionate ions. It has a role as a food preservative and an antifungal drug. It contains a propionate.

CAS Number137-40-6
PubChem CID2723816
IUPAC Namesodium propanoate
Molecular FormulaC3H5NaO2
Molecular Weight96.06
Topological Polar Surface Area40.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count6
Formal Charge0
Complexity44
SMILES
CCC(=O)[O-].[Na+]
InChI
InChI=1S/C3H6O2.Na/c1-2-3(4)5;/h2H2,1H3,(H,4,5);/q;+1/p-1
InChIKey
JXKPEJDQGNYQSM-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of Sodium Propionate
CAS: 137-40-6
CID: 2723816
Formula: C3H5NaO2
MW: 96.06
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight96.06
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass96.01872368
Monoisotopic Mass96.01872368
Topological Polar Surface Area40.1 Ų
Heavy Atom Count6
Formal Charge0
Complexity44.1
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-125561Josamycin propionate
HY-W011180-01Vitamin A Propionate
HY-B0878-01Halobetasol propionate
HY-156074Erythromycin propionate
HY-W013128Cholesteryl propionate
HY-137173Laidlomycin propionate
HY-137920-01Salvinorin A propionate
HY-13600-01Clobetasol propionate
HY-41616-01Methoxymethyl propionate
HY-B0154-01Fluticasone (propionate)

Alternative Products

CatalogName
sc-251043Sodium propionate
466327-01Sodium Propionate Hydrate
TRC-S673290-10MGSodium Propionate-13C3
LC-10553.1Sodium propionate pure
TRC-S667066-10MGSodium Propionate-d5
DE2155Sodium Propionate-D3
sc-251046Sodium propionate-2-13C
02493 00500Sodium propionate 98% Extrapure
33650-01Sodium Propionate pure, 99%

Popular Products