Products for Research Use Only
RegisterLogin

NJH-2-056

CAT: 0804-HY-143344-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-143344-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NJH-2-056 is a deubiquitinase-targeting chimera (DUBTAC) linking the OTUB1 recruiter EN523 to the CFTR chaperone lumacaftor. NJH-2-056 can be used for cystic fibrosis research[1].
CAS Number
2858812-69-6
UNSPSC
12352005
Target
CFTR; PROTACs
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/njh-2-056.html
Purity
98.23
Solubility
DMSO : ≥ 100 mg/mL
Smiles
C=CC(N1CCN(C(C1)=O)C2=CC=C(O2)CCC(NCCCNC(C3=CC=CC(C4=NC(NC(C5(CC5)C6=CC=C7OC(F)(OC7=C6)F)=O)=CC=C4C)=C3)=O)=O)=O
Molecular Formula
C41H40F2N6O8
Molecular Weight
782.79
References & Citations
[1]Henning NJ, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022 Apr;18 (4) :412-421.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-115878-01NJH-2-057
HY-143348-01NJH-2-030
HY-W011060-01Cryptand 2.2.2
HY-B1500-012,2,2-Trichloroethanol
HY-W0733142,2,2-Trifluoroethoxyamine (hydrochloride)
HY-N2048-012,2':5',2''-Terthiophene
HY-132268-01Cav 2.2 blocker 2
HY-B1500R-012,2,2-Trichloroethanol (Standard)
HY-W011060R-01Cryptand 2.2.2 (Standard)
HY-Z8487-012- (2-Chlorophenyl) -2-hydroxycyclohexanone

Alternative Products

CatalogName
BA6625-5NJH-2-056
BA6618-10NJH-2-057
T61521-01NJH-2-030
GTR19213217NJH-2-075
BUP02351-01CTA 056
GTR19154292-01M351-056
A17192-100CTA 056 100mg
A17192-10CTA 056 10mg
A17192-2CTA 056 2mg
A17192-50CTA 056 50mg

Popular Products