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BDNF Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335687-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335687-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Neurotrophins function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF), originally discovered in the 1950s as a soluble peptide promoting the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3) and neurotrophin-4 (NT-4) (also designated NT-5) .
Product Name Alternative
BDNF; MGC34632; Abrineurin; ANON2; Brain Derived Neurotrophic Factor; Neurotrophin; BULN2
UniProt
P23560
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human BDNF
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P23560

Neurotrophic factor BDNF precursor form

BDNF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P23560
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BDNF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
proBDNF
EC number
—
Processing
Precursor
Secondary accessions
A7LA85, A7LA92, D3DQZ2, Q598Q1, Q6DN19, Q6YNR2, Q6YNR3, Q9BYY7, Q9UC24
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative promoter usageAlternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Molecular function

Growth factor

Cellular component

Secreted

Domain

Signal

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