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Cdc23/APC8 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335237-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335237-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16) . APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth.
Product Name Alternative
CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8
UniProt
Q9UJX2
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Cdc23/APC8
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 ICC/IF 1:50~1:100
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · Q9UJX2

Cell division cycle protein 23 homolog

CDC23_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UJX2
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CDC23
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K6E5, B4E3A2, B7WP05, D3DQB7, O75433, Q53FN2, Q9BS73
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionMitosisUbl conjugation pathway

Domain

RepeatTPR repeat

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