Products for Research Use Only

Src Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335167-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335167-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells (1) . Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects.
Product Name Alternative
EC 2.7.10.2; p60-Src; c-Src; pp60; c-src
UniProt
P12931
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Src
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 FC 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P12931

Proto-oncogene tyrosine-protein kinase Src

SRC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P12931
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SRC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.10.2
Processing
—
Secondary accessions
E1P5V4, Q76P87, Q86VB9, Q9H5A8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Biological process

Cell adhesionCell cycleHost-virus interactionImmunity

Cellular component

Cell junctionCell membraneCytoplasmCytoskeletonMembraneMitochondrionMitochondrion inner membraneNucleus

Disease

Disease variantProto-oncogene

Molecular function

KinaseTransferaseTyrosine-protein kinase

PTM

LipoproteinMyristatePhosphoproteinUbl conjugation

Domain

SH2 domainSH3 domain

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