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VAMP2 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335018-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335018-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The SNARE complex is involved in vesicular transport and membrane fusion, a process regulated by calcium. In neurons, VAMP2 is predominantly inserted in presynaptic vesicle membranes. Assembly of VAMP2 with the plasma membrane SNAREs syntaxin 1 and SNAP25 is a key event necessary for membrane fusion and neurotransmitter release.
Product Name Alternative
RATVAMPB; RATVAMPIR; SYB2; Synaptobrevin 2; Vamp2l; Vesicle-associated membrane protein 2 (synaptobrevin 2)
UniProt
P63027
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human VAMP2
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Neuroscience
Purification
Affinity-chromatography
Dilution
WB 1:1000~1:5000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
FC, ICC, IP, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P63027

Vesicle-associated membrane protein 2

VAMP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P63027
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
VAMP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VAMP-2
EC number
—
Processing
—
Secondary accessions
P19065, Q9BUC2
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Cellular component

Cell membraneCytoplasmic vesicleMembraneSynapse

Domain

Coiled coilTransmembraneTransmembrane helix

Disease

Disease variantIntellectual disability

Biological process

ExocytosisNeurotransmitter transportTransport

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