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Human Interferon-γ (IFN-γ) ELISPOT Kit

CAT: 0716-RAS-SP001-96testsSize: 96 TestsDry Ice: NoHazardous: No
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CAT#:0716-RAS-SP001-96testsSize:96 Tests
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interferon-gamma (IFN-γ/IFNG) is a dimerized soluble cytokine that is the only member of the type II class of interferon. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-γ belongs. IFN-gamma has been used in a wide variety of clinical indications. Interferon-gamma (IFNgamma) is a central regulator of the immune response and signals via the Janus Activated Kinase (JAK)-Signal Transducer and Activator of Transcription (STAT) pathway. Interferon gamma has broader roles in activation of innate and adaptive immune responses to viruses and tumors, in part through upregulating transcription of genes involved in cell cycle regulation, apoptosis, and antigen processing/presentation. Despite this, rodent and human trophoblast cells show dampened responses to IFNG that reflect the resistance of these cells to IFNG-mediated activation of major histocompatibility complex (MHC) class II transplantation antigen expression.
Description
Human Interferon-γ (IFN-γ) ELISPOT Kit is expressed from Human -.
Reactivity
Human
Target
IFN-gamma
Applications
This kit is used to detect IFN-γ at the cellular level.
Stability
The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C.
Format
Solid
Components
ELISpot assays employ the quantitative sandwich enzyme-linked immunosorbent assay (ELISA) technique. The Kit consists of Pre-coated Anti-IFN-γ Antibody Microplate, Positive Stimulus, Biotin-Anti-IFN-γ Antibody, Streptavidin-HRP, AEC and buffers.
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Blue ice
Storage Conditions
2-8°C
Package Size
96tests*1
Species
Human

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