Products for Research Use Only

CBS Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18334532-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR18334532-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
Product Name Alternative
HIP4; CBS
UniProt
P35520
Reactivity
Human
Immunogen
A synthesized peptide derived from human CBS
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P35520

Cystathionine beta-synthase

CBS_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35520
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CBS
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
4.2.1.22
Processing
—
Secondary accessions
B2R993, D3DSK4, Q99425, Q9BWC5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Allosteric enzymeLyase

Coding sequence diversity

Alternative splicing

Biological process

Amino-acid biosynthesisCysteine biosynthesis

Domain

CBS domain

Cellular component

CytoplasmNucleus

Disease

Disease variant

Ligand

HemeIronMetal-bindingPyridoxal phosphate

PTM

Isopeptide bondPhosphoproteinUbl conjugation