STE-MEK1 (13)

CAT: 0804-HY-P5977Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P5977Size:1 Each
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Description
STE-MEK1 (13) (Ste-MPKKKPTPIQLNP-NH) is a cell permeable ERK1/2 inhibitor (IC50: 13-30 μM) . STE-MEK1 (13) inhibits ERK1/2 phosphorylation[1][2].
CAS Number
[566872-15-9]
Product Name Alternative
Ste-MPKKKPTPIQLNP-NH₂; ERK Activation Inhibitor Peptide
UNSPSC
12352209
Target
ERK
Type
Peptides
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ste-mek1-13.html
Solubility
10 mM in DMSO
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@@H]([C@H](O)C)C(N(CCC2)[C@@H]2C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(N)=O)C(N(CCC3)[C@@H]3C(N)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCC4)N4C([C@H](CCSC)NC(CCCCCCCCCCCCCCCCC)=O)=O)=O)=O)=O
Molecular Formula
C86H153N19O17S
Molecular Weight
1757.32
References & Citations
[1]Li G, et al. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec;13 (12) :2109-17.|[2]Whiteman M, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006 May;14 (5) :460-70.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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