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Prostaglandin D2

CAT: 0804-HY-101988-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101988-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Prostaglandin D2 (PGD2) is one of the major PGs actively produced in the brain of various mammals[1]. Prostaglandin D2 is one of the most potent endogenous sleep promoting substances[2]. PGD2 plays a protective role by suppressing inflammation[3].
CAS Number
41598-07-6
Product Name Alternative
PGD2
UNSPSC
12352211
Hazard Statement
H302, H361
Target
Endogenous Metabolite; Prostaglandin Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Prostaglandin_D2.html
Purity
99.5
Solubility
Ethanol : 75 mg/mL (ultrasonic; warming)
Smiles
CCCCC[C@H](O)/C=C/[C@@H]1[C@H]([C@@H](O)CC1=O)C/C=C\CCCC(O)=O
Molecular Formula
C20H32O5
Molecular Weight
352.47
Precautions
H302, H361
References & Citations
[1]Suzuki F, et al. Transport of prostaglandin D2 into brain. Brain Res. 1986 Oct 22;385 (2) :321-8.|[2]Zhang BJ, et al. Adenosine A2A receptor deficiency attenuates the somnogenic effect of prostaglandin D2 in mice. Acta Pharmacol Sin. 2017 Apr;38 (4) :469-476.|[3]Kida T, et al. Prostaglandin D2 Attenuates NSC 125066-Induced Lung Inflammation and Pulmonary Fibrosis. PLoS One. 2016 Dec 19;11 (12) :e0167729.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Phase 1
Isoform
DP; Human Endogenous Metabolite

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