STAT3-IN-17
CAT:
804-HY-148706-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
STAT3-IN-17
- CAS Number: 1245814-52-1
- UNSPSC Description: STAT3-IN-17 is a moderate STAT3 inhibitor (IC50=0.7 μM; HEK-Blue IL-6), with antiproliferative activity in HeLa cells. STAT3-IN-17 has good pharmacokinetic characteristics. STAT3-IN-17 also inhibits pyruvate-ferredoxin oxidoreductase (PFOR), and inhibits Helicobacter pylori[1][2].
- Target Antigen: STAT
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Cancer; Infection
- Assay Protocol: https://www.medchemexpress.com/stat3-in-17.html
- Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=C(C(F)(F)F)C=C2
- Molecular Weight: 317.24
- References & Citations: [1]Lü Z, et al. Structure-Activity Study of Nitazoxanide Derivatives as Novel STAT3 Pathway Inhibitors. ACS Med Chem Lett. 2021 Apr 1;12(5):696-703.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported