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Human CellExp™ IL-5, Human Recombinant

CAT: 0026-P1486-10Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0026-P1486-10Size:10 µg
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Description
Interleukin-5 (IL-5) is identified by its ability to support the growth and terminal differentiation of mouse B cells to immunoglobulin secreting cells. IL-5 also exerts pleiotropic activities on various target cells including eosinophils and basophils via receptors of IL-5-specific α and common β-subunit. IL-5’s stimulation of eosinophil has been implicated in the pathogenesis of allergic inflammatory diseases, such as asthma. Targeting the interleukin-5 pathway offers benefit to patients with severe asthma. Mepolizumab is an anti-interleukin-5 (IL-5) humanized monoclonal antibody that has been approved as an add-on biological treatment for severe eosinophilic asthma, by both the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA).
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
12 months

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