FDI-6
CAT:
804-HY-112721-01
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FDI-6
- CAS Number: 313380-27-7
- UNSPSC Description: FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.
- Target Antigen: DNA/RNA Synthesis
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/FDI-6.html
- Purity: 99.65
- Solubility: DMSO : 41.67 mg/mL (ultrasonic)
- Smiles: O=C(C1=C(N)C2=C(C(F)(F)F)C=C(C3=CC=CS3)N=C2S1)NC4=CC=C(F)C=C4
- Molecular Weight: 437.43
- References & Citations: [1]Gormally MV, et al. Suppression of the FOXM1 transcriptional programme via novel small molecule inhibition. Nat Commun. 2014 Nov 12;5:5165.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported