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BEST2 rabbit pAb

CAT: 0855-ES20818-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20818-01Size:50 µL
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Background
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008]
Description
This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. [provided by RefSeq, Jul 2008],
UniProt
Q8NFU1
Swiss Prot
Q8NFU1
Reactivity
Mouse; Rat
Immunogen
Synthetic Peptide of BEST2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF
Dilution
WB: 1:500-1000 IHC: 1:200-500
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1
Gene ID (Human)
54831

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