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LIS1 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18335501-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18335501-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors.
Product Name Alternative
LIS1; LIS2; MDCR; MDS; PAFAH alpha; PAFAH; PAFAH1B1; PAFAHA
UniProt
P43034
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human LIS1
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Purification
Affinity-chromatography
Dilution
WB 1:500~1:2000
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · P43034

Platelet-activating factor acetylhydrolase IB subunit beta

LIS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P43034
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PAFAH1B1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R7Q7, Q8WZ88, Q8WZ89
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Biological process

Cell cycleCell divisionDifferentiationLipid degradationLipid metabolismMitosisNeurogenesisTransport

Domain

Coiled coilRepeatWD repeat

Cellular component

CytoplasmCytoskeletonMembraneMicrotubuleNucleus

Molecular function

Developmental protein

Disease

Disease variantLissencephaly

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