hMAO-B-IN-4
CAT:
804-HY-152671-01
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
hMAO-B-IN-4
- CAS Number: 1666119-75-0
- UNSPSC Description: hMAO-B-IN-4 (compound B10) is a selective, reversible and blood–brain barrier (BBB) penetrable human monoamine oxidase-B (hMAO-B) inhibitor with an IC50 value and a Ki value of 0.067 and 0.03 μM, respectively. hMAO-B-IN-4 inhibits hMAO-A with an IC50 value of 33.82 μM. hMAO-B-IN-4 can be used for Alzheimer’s disease (AD) and Parkinson’s disease (PD) research[1].
- Target Antigen: Monoamine Oxidase
- Type: Reference compound
- Related Pathways: Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/hmao-b-in-4.html
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(C1=CC=CS1)/C=C/C2=CC=C(C=C2)OCC3=CC=CC=C3
- Molecular Weight: 320.40
- References & Citations: [1]Sudevan ST, et al. Introduction of benzyloxy pharmacophore into aryl/heteroaryl chalcone motifs as a new class of monoamine oxidase B inhibitors. Sci Rep. 2022 Dec 27;12(1):22404.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported