c-Fms-IN-3

c-Fms-IN-3

• CAS Number: 885704-21-2
• UNSPSC Description: c-Fms-IN-3 is a novel c-Fms kinase inhibitor with a potential as anti-inflammatory agent and antirheumatic agent.
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/c-FMS-inhibitor.html
• Purity: 99.69
• Solubility: DMSO : 25 mg/mL (ultrasonic)
• Smiles: CN(CC1)CCN1C2=CC=C(NC(C3=CC(C#N)=CN3)=O)C(N4CCC(C)CC4)=C2
• Molecular Weight: 406.52
• References & Citations: [1]Meegalla, Sanath K.; Wall, Mark J.; Chen, Jinsheng et al. Structure-based optimization of a potent class of arylamide FMS inhibitors. Bioorganic & Medicinal Chemistry Letters (2008), 18(12), 3632-3637.|[2]Illig, Carl R.; Chen, Jinsheng; Wall, Mark J. et al. Discovery of novel FMS kinase inhibitors as anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters (2008), 18(5), 1642-1648.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported