HCoV-229E-IN-1

• UNSPSC Description:

  HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hcov-229e-in-1.html

• Purity:

  99.16

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic)

• Smiles:

  C=C([C@@H]1CC[C@@]2(CC[C@]3([C@@]4(CC[C@]5(C(C)(C6=C(C[C@@]5([C@]4(CC[C@@]3([C@]21[H])[H])[H])C)N=NN6[C@H](C7=CC=CC=C7)C)C)[H])C)C)C(O)=O)C

• Molecular Weight:

  583.85

• References & Citations:

  [1]Stevaert A, et, al. Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15 Endoribonuclease. J Med Chem. 2021 May 13;64(9):5632-5644.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2639757-13-2