HCoV-OC43-IN-1

• UNSPSC Description:

  HCoV-OC43-IN-1 (Compound IV-16) is a coronavirus HCoV-OC43 inhibitor. HCoV-OC43-IN-1 has antiviral efficacy (EC50: 90 nM). HCoV-OC43-IN-1 inhibits the mRNA level and expression of viral nucleocapsid protein (NP)[1].

• Target Antigen:

  SARS-CoV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/hcov-oc43-in-1.html

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  FC(F)(C1=CC(NC2=C3C=C(OCC)C=CC3=NC(NCC4OCCC4)=N2)=CC(C(F)(F)F)=C1)F

• Molecular Weight:

  500.44

• References & Citations:

  [1]Zhou S, et al. Design, synthesis, and structure-activity relationships of a novel class of quinazoline derivatives as coronavirus inhibitors. Eur J Med Chem. 2023 Sep 25;261:115831.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2809363-81-1