PU-WS13

• UNSPSC Description:

  PU-WS13 is a selective Grp94 inhibitor, with an EC50 of 0.22 μM.

• Target Antigen:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/PU-WS13.html

• Purity:

  99.82

• Solubility:

  DMSO : ≥ 40 mg/mL

• Smiles:

  CC(NCCCN1C(SC2=CC(Cl)=CC(Cl)=C2)=NC3=C(N)N=CN=C13)C

• Molecular Weight:

  411.35

• References & Citations:

  [1]Patel PD, et al. Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat Chem Biol. 2013 Nov;9(11):677-684.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1454619-14-7