PU.1-IN-1

• UNSPSC Description:

  PU.1-IN-1 (compound A11) is a potent PU.1 inhibitor with an IC50 of 2 nM. PU.1-IN-1 has anti-inflammatory properties[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pu-1-in-1.html

• Purity:

  97.13

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=S(C1=CC=C(C2CCCCC2)C=C1)(NCC3=CC=NC=C3)=O

• Molecular Weight:

  330.44

• References & Citations:

  [1]Li-Huei Tsai, et al. Systems and assays for identifying pu.1 inhibitors. WO2021051016A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  873588-27-3