DBCO-amine
CAT:
804-HY-W000423-03
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
DBCO-amine
- CAS Number: 1255942-06-3
- UNSPSC Description: DBCO-amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-amine is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/dbco-amine.html
- Purity: 99.91
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCN
- Molecular Weight: 276.34
- References & Citations: [1]Ermira Pazolli, et al. Splicing modulator antibody-drug conjugates and methods of use. WO2019232449A1.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, protect from light)
- Clinical Information: No Development Reported