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Oxitropium (Bromide)

CAT: 0804-HY-U00105Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-U00105Size:1 Each
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Description
Oxitropium bromide is an mAChR antagonist used as an anticholinergic bronchodilator agent for the treatment of asthma and chronic obstructive pulmonary disease.
CAS Number
30286-75-0
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Oxitropium_Bromide.html
Solubility
10 mM in DMSO
Smiles
CC[N@@+]1([C@H]2[C@@H](O3)[C@@H]3[C@@H]1C[C@H](OC([C@@H](C4=CC=CC=C4)CO)=O)C2)C.[Br-]
Molecular Formula
C19H26BrNO4
Molecular Weight
412.32
References & Citations
[1]Shindoh C, et al. Effects of inhalation or incubation of oxitropium bromide on diaphragm muscle contractility in mice. Allergol Int. 2011 Sep;60 (3) :365-72.|[2]Kohno SW, et al. Effect of oxitropium bromide (Ba253) on increased airway resistance induced by various agonists and antigen in the guinea pig. Jpn J Pharmacol. 1989 Aug;50 (4) :455-66.|[3]Takeyama K, et al. Effect of oxitropium bromide on histamine-induced airway goblet cell secretion. Am J Respir Crit Care Med. 1996 Jul;154 (1) :231-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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O847165Oxitropium Bromide
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