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Alagebrium (bromide)

CAT: 0804-HY-106024ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-106024ASize:1 Each
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Description
Alagebrium bromide is an analog of Alagebrium Chloride , a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF).
CAS Number
181069-80-7
Product Name Alternative
ALT711 (bromide)
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/alagebrium-bromide.html
Smiles
O=C(C1=CC=CC=C1)C[N+]2=CSC(C)=C2C.[Br-]
Molecular Formula
C13H14BrNOS
Molecular Weight
312.23
References & Citations
[1]Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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