Alagebrium (bromide)

• Description:

  Alagebrium bromide is an analog of Alagebrium Chloride (HY-106024B), a glucose cross-link blocker. Alagebrium Chloride disrupts glucose cross-links and may improve ventricular and arterial compliance. Alagebrium Chloride improves left ventricular diastolic filling and has the potential to inhibit diastolic heart failure (DHF) .

• Product Name Alternative:

  ALT711 (bromide)

• UNSPSC:

  12352005

• Target:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/alagebrium-bromide.html

• Smiles:

  O=C(C1=CC=CC=C1)C[N+]2=CSC(C)=C2C.[Br-]

• Molecular Formula:

  C13H14BrNOS

• Molecular Weight:

  312.23

• References & Citations:

  [1]Attenuation of Extracellular Matrix Accumulation in Diabetic Nephropathy by the Advanced Glycation End Product Cross-Link Breaker ALT-711 via a Protein Kinase C-α−Dependent Pathway

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 3

• CAS Number:

  181069-80-7