Cetirizine Impurity C (dihydrochloride)

Cetirizine Impurity C (dihydrochloride)

• CAS Number: 2702511-37-1
• UNSPSC Description: Cetirizine Impurity C dihydrochloride is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Field of Research: Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cetirizine-impurity-c-dihydrochloride.html
• Purity: 99.95
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 83.33 mg/mL (ultrasonic)
• Smiles: O=C(O)COCCN1CCN(C(C2=CC=CC=C2Cl)C3=CC=CC=C3)CC1.[H]Cl.[H]Cl
• Molecular Weight: 461.81
• References & Citations: [1]Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5.|[2]Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported