Cetirizine Impurity C

Cetirizine Impurity C

• CAS Number: 83881-59-8
• UNSPSC Description: Cetirizine Impurity C is an impurity of Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist[1][2].
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/cetirizine-impurity-c.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)COCCN1CCN(C(C2=CC=CC=C2Cl)C3=CC=CC=C3)CC1
• Molecular Weight: 388.89
• References & Citations: [1]Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5.|[2]Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported