7β-Hydroxybufalin

• UNSPSC Description:

  7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase[1].

• Target Antigen:

  Cholinesterase (ChE); Glycosidase

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease;Neuronal Signaling

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/7β-hydroxybufalin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@@]([C@@]12C)(CC[C@]1([H])C(C=C3)=COC3=O)[C@@]([C@H](C[C@]4([H])C[C@H]5O)O)([H])[C@@](CC2)([H])[C@]4(CC5)C

• Molecular Weight:

  402.52

• References & Citations:

  [1]Jian Xiao, et al. Bufadienolides from the Venom of Bufo Bufo gargarizans and Their Enzyme Inhibition Activities and Brine Shrimp Lethality. Natural Product Communications. 2018. Vol.13. No.7:827-830.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  20143-97-9