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TPA-NAC

CAT: 0804-HY-157779Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-157779Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TPA-NAC is a nonfluorogenic prodrug by introducing N-acetyl-L-cysteine (NAC) into a conjugated acceptor skeleton. TPA-NAC is capable of fluorogenic selective labeling of HSA[1].
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/tpa-nac.html
Solubility
10 mM in H2O
Smiles
OC([C@@H](NC(C)=O)CS/C(SC[C@@H](NC(C)=O)C(O)=O)=C1C(C2=CC(C3=CC=C(N(C4=CC=CC=C4)C5=CC=CC=C5)C=C3)=CC=C2C\1=O)=O)=O
Molecular Formula
C38H33N3O8S2
Molecular Weight
723.81
References & Citations
[1]Tianhong Wu, et al. A Rationally Designed Prodrug for the Fluorogenic Labeling of Albumin and Theranostic Effects on Drug-Induced Liver Injury. Anal Chem. 2024 Feb 16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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