malonyl-NAC

CAT:

804-HY-157395-03

Size:

25 mg

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CAS Number: 2361327-06-0
UNSPSC Description: malonyl-NAC increases cellular propylation, resulting in reduced endogenous GAPDH activity. malonyl-NAC increases GAPDH malonylation in cells and inhibits pyruvate kinase activity. In addition, malonyl-NAC limits the metabolism and proliferation of a highly glycolytic kidney cancer cell line harboring a tricarboxylic acid cycle mutation[1].
Target Antigen: Others
Type: Reference compound
Related Pathways: Others
Applications: Cancer-Kinase/protease
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/malonyl-nac.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: O=C(CC(SCCNC(C)=O)=O)OCC
Molecular Weight: 233.28
References & Citations: [1]Kulkarni RA, et al. Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling. Cell Chem Biol. 2017 Feb 16;24(2):231-242.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-157395-04	malonyl-NAC
HY-157395-01	malonyl-NAC
HY-157395-02	malonyl-NAC
HY-157395-03	malonyl-NAC
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HY-136408-01	Malonyl CoA (lithium)
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