Products for Research Use Only
RegisterLogin

Methisazone

CAT: 0804-HY-124564-02Size: 10 mM - 1 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-124564-02Size:10 mM - 1 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Methisazone (Marboran) is an antiviral agent that works by inhibiting mRNA and protein synthesis. Methisazone is also a SARS-CoV-2 (COVID-19) inhibitor. Methisazone is mainly used in pox viruses[1].
CAS Number
1910-68-5
Product Name Alternative
Marboran
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Orthopoxvirus; SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/methisazone.html
Purity
98.26
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N(C2=C(/C1=N/NC(N)=S)C=CC=C2)C
Molecular Formula
C10H10N4OS
Molecular Weight
234.28
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Bhumi Shah, et al. In silico studies on therapeutic agents for COVID-19: Drug repurposing approach. Life Sci. 2020 Jul 1;252:117652.|[2]Smee DF, et, al. Progress in the discovery of compounds inhibiting orthopoxviruses in animal models. Antivir Chem Chemother. 2008;19 (3) :115-24.|[3]Quenelle D C, et al. In vitro and in vivo evaluation of isatin-β-thiosemicarbazone and marboran against vaccinia and cowpox virus infections[J]. Antiviral Research, 2006, 71 (1) : 24-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Methisazone

Metisazone is a member of indoles.

CAS Number1910-68-5
PubChem CID667492
IUPAC Name(2-hydroxy-1-methylindol-3-yl)iminothiourea
Molecular FormulaC10H10N4OS
Molecular Weight234.28
XLogP2
Topological Polar Surface Area108
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count16
Formal Charge0
Complexity309
SMILES
CN1C2=CC=CC=C2C(=C1O)N=NC(=S)N
InChI
InChI=1S/C10H10N4OS/c1-14-7-5-3-2-4-6(7)8(9(14)15)12-13-10(11)16/h2-5,15H,1H3,(H2,11,16)
InChIKey
TTZUCVNWOZLIGL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Methisazone
CAS: 1910-68-5
CID: 667492
Formula: C10H10N4OS
MW: 234.28
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight234.28
XLogP32
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass234.05753213
Monoisotopic Mass234.05753213
Topological Polar Surface Area108 Ų
Heavy Atom Count16
Formal Charge0
Complexity309
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-B0208-01Methimazole
HY-B0208SMethimazole-d3
HY-B0208R-01Methimazole (Standard)

Alternative Products

CatalogName
T24455-01Methisazone

Popular Products