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Methimazole (Standard)

CAT: 0804-HY-B0208R-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0208R-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Methimazole (Standard) (Thiamazole (Standard) ) is the analytical standard of Methimazole. This product is intended for research and analytical applications. Methimazole (Thiamazole) is an anti-thyroid agent, which blocks thyroid hormone production from the thyroid gland. Metamizol can cause hepatotoxicity.
CAS Number
60-56-0
Product Name Alternative
Thiamazole (Standard)
UNSPSC
12352005
Hazard Statement
H302-H315-H317-H319-H335-H361
Target
Reference Standards; Thyroid Hormone Receptor
Type
Reference Standards
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/methimazole-standard.html
Smiles
S=C1NC=CN1C
Molecular Formula
C4H6N2S
Molecular Weight
114.17
Precautions
P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Heidari R, et, al. Effects of Enzyme Induction and/or Glutathione Depletion on Methimazole-Induced Hepatotoxicity in Mice and the Protective Role of N-Acetylcysteine. Adv Pharm Bull. 2014;4 (1) :21-8.|[2]Crescioli C, et al. Methimazole inhibits CXC chemokine ligand 10 secretion in human thyrocytes. J Endocrinol. 2007 Oct;195 (1) :145-55.|[3]Tatara MR, et al. Effects of long-term oral administration of methimazole on femur and tibia properties in male Wistar rats. Biomed Pharmacother. 2017 Oct;94:124-128.|[4]Reza Heidari, et al. Mechanisms of methimazole cytotoxicity in isolated rat hepatocytes. Drug Chem Toxicol. 2013 Oct;36 (4) :403-11.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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