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FE65 Rabbit mAb [KD Validated] Antibody

CAT: 0013-GTR18301904-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR18301904-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis.
Product Name Alternative
APBB1; Protein Fe65; RIR
UniProt
O00213
Reactivity
Human
Immunogen
A synthesized peptide derived from human FE65
Clonality
Monoclonal
Conjugation
Unconjugated
Source
Recombinant Rabbit
Field of Research
Cell Biology
Purification
Affinity-chromatography
Dilution
WB:1:500~1:2000IHC:1:50~1:200ICC/IF:1:50~1:200
Form
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Molecular Weight
100kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ICC, IHC, WB
Host or Source
Rabbit
Isotype
Rabbit IgG

UniProtKB · O00213

Amyloid beta precursor protein binding family B member 1

APBB1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00213
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APBB1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A1E379, A6NH82, A6NL69, B7Z1J5, B7Z1J6, B7Z2Y0, D3DQT2, Q7Z324, Q96A93, V9GYK0, V9GYT4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Molecular function

ActivatorChromatin regulatorRepressor

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDNA damageTranscriptionTranscription regulation

Cellular component

Cell membraneCell projectionCytoplasmMembraneNucleus

Domain

Repeat

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