DAS-5-oCRBN

CAT:

804-HY-163144-03

Size:

10 mg

Price:

Ask

For price, please contact [email protected]

UNSPSC Description: DAS-5-oCRBN is a selective and potent PROTAC degrader of c-Src kinase. DAS-5-oCRBN has antiproliferative activity in both c-Src-dependent cell lines[1].
Target Antigen: PROTACs; Src
Type: Reference compound
Related Pathways: PROTAC;Protein Tyrosine Kinase/RTK
Applications: Cancer-Kinase/protease
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/das-5-ocrbn.html
Solubility: DMSO : 100 mg/mL (ultrasonic)
Smiles: CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(CC(N5CCN(C6=C7C(N(C8CCC(NC8=O)=O)C(C7=CC=C6)=O)=O)CC5)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1
Molecular Weight: 826.32
References & Citations: [1]Mao W, et al. Selective and Potent PROTAC Degraders of c-Src Kinase. ACS Chem Biol. 2024 Jan 19;19(1):110-116.
Shipping Conditions: Room Temperature
Clinical Information: No Development Reported

Cat	Name
HY-163144-03	DAS-5-oCRBN
HY-163144-02	DAS-5-oCRBN
HY-163144-01	DAS-5-oCRBN
HY-154346	5’-Azido-5’-deoxy-5-methyluridine
HY-154344	5′-Deoxy-5′-iodo-5-methyluridine
HY-154345	4′,5′-Didehydro-5′-deoxy-5-methyluridine
HY-154054	5′-Azido-5′-deoxyadenosine
HY-N11867A	5(S)-5-Carboxystrictosidine
HY-148038-05	5-HT3 antagonist 5
HY-148038-01	5-HT3 antagonist 5

Cat	Name
11.CIR.K.2	INgezim PCV DAS
12.BVD.K.2	INgezim BVD DAS
11.CIR.K.2/2	INgezim PCV DAS
12.BVD.K.2/5	INgezim BVD DAS
TBS43007-100	DAS-59132 qPCR Detection
149188	BWS-DAS-CD AE Software
149187	BWS-DAS-EM AE Software
CABT-L4607	Mouse Anti-Diacetoxyscirpenol monoclonal antibody, clone DAS
MBS1098790	Recombinant Pichia angusta Dihydroxyacetone synthase (DAS), partial
MBS6100521-02	5'-Deoxy-5-fluorouridine (5'dUrd, 5-Fluoro-5'-deoxyuridine)