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Griseofulvin-d3

CAT: 0804-HY-17583S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17583S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].
CAS Number
1279033-22-5
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Antibiotic; Apoptosis; Endogenous Metabolite; Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease; Others
Field of Research
Infection; Cancer
Solubility
10 mM in DMSO
Smiles
O=C1[C@]2(C(OC([2H])([2H])[2H])=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C31
Molecular Formula
C17H14D3ClO6
Molecular Weight
355.78
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Brilhante RSN, et al. In vitro activity of azole derivatives and griseofulvin against planktonic and biofilm growth of clinical isolates of dermatophytes. Mycoses. 2018 Jul;61 (7) :449-454.|[3]Schmeel LC, et al. Griseofulvin Efficiently Induces Apoptosis in In Vitro Treatment of Lymphoma and Multiple Myeloma. Anticancer Res. 2017 May;37 (5) :2289-2295.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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