Genistin

CAT: 0804-HY-N0595-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0595-01Size:5 mg
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Description
Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway[1][2][3].
CAS Number
[529-59-9]
Product Name Alternative
Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Estrogen Receptor/ERR
Type
Natural Products
Related Pathways
Apoptosis; Vitamin D Related/Nuclear Receptor
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Genistin.html
Purity
98.05
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C(C1=CC=C(O)C=C1)=COC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)C2=C4O
Molecular Formula
C21H20O10
Molecular Weight
432.38
Precautions
H302, H315, H319, H335
References & Citations
[1]Choi YR, et al. Genistin: A Novel Potent Anti-Adipogenic and Anti-Lipogenic Agent. Molecules. 2020;25 (9) :2042. Published 2020 Apr 27.|[2]Liang Y, et al. A Comprehensive Screening and Identification of Genistin Metabolites in Rats Based on Multiple Metabolite Templates Combined with UHPLC-HRMS Analysis. Molecules. 2018;23 (8) :1862. Published 2018 Jul 26.|[3]Hwang ST, et al. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [published online ahead of print, 2020 Oct 16]. Life Sci. 2020;263:118594.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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