VMY-2-95

CAT: 0804-HY-120946Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-120946Size:1 Each

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Description

VMY-2-95 is an oral active and blood-brain barrier (BBB) penetrant α4β2 nicotinic acetylcholine receptor desensitizer. VMY-2-95 can be used for study of depression or addiction[1][2].

CAS Number

1434047-61-6

UNSPSC

12352005

Target

NAChR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/vmy-2-95.html

Smiles

C1(OC[C@@H]2CCN2)=CC(C#CC3=CC=CC=C3)=CN=C1

Molecular Formula

C17H16N2O

Molecular Weight

264.32

References & Citations

[1]Kong H, et al. Preclinical studies of the potent and selective nicotinic α4β2 receptor ligand VMY-2-95. Mol Pharm. 2015;12 (2) :393-402. |[2]Yenugonda VM, et al. Design, synthesis and discovery of picomolar selective α4β2 nicotinic acetylcholine receptor ligands. J Med Chem. 2013;56 (21) :8404-8421.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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