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Acyclovir triphosphate (sodium)

CAT: 0804-HY-142028A-01Size: 5 mg (100 mM x 100 μL in water)Dry Ice: NoHazardous: No
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CAT#:0804-HY-142028A-01Size:5 mg (100 mM x 100 μL in water)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acyclovir triphosphate (Synonyms: AcycloGTP) sodium is a Acyclovir derivative that competitively inhibits viral DNA polymerase by acting as an analog to deoxyguanosine triphosphate (dGTP). Acyclovir triphosphate sodium is an inhibitor of HIV-1 reverse transcriptase. Acyclovir triphosphate sodium causes termination of viral DNA synthesis[1].
CAS Number
221119-43-3
Product Name Alternative
AcycloGTP (sodium)
UNSPSC
12352200
Target
DNA/RNA Synthesis; HIV; Nucleoside Antimetabolite/Analog; Reverse Transcriptase
Type
Biochemical Assay Reagents
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/acyclovir-triphosphate-sodium.html
Concentration
100 mM * 500 μL in water
Purity
99.71
Smiles
O=P(OP(OP(OCCOCN1C(N=C(N)NC2=O)=C2N=C1)(O)=O)(O)=O)(O)O.[x].[Na]
Molecular Formula
C8H14N5O12P3.xNa
References & Citations
[1]Hirsch MS, et al. Drug therapy: antiviral agents (second of two parts) . N Engl J Med. 1980 Apr 24;302 (17) :949-53. |[2]McMahon MA, et al. Consistent inhibition of HIV-1 replication in CD4+ T cells by acyclovir without detection of human herpesviruses. J Virol. 2011 May;85 (9) :4618-22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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