Propargyl-PEG2-acid

CAT:

804-HY-118764-02

Size:

250 mg

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CAS Number: 1859379-85-3
UNSPSC Description: Propargyl-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Target Antigen: ADC Linker; PROTAC Linkers
Type: ADC Related
Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/propargyl-peg2-acid.html
Purity: 98.0
Solubility: DMSO : 250 mg/mL (ultrasonic)
Smiles: O=C(O)CCOCCOCC#C
Molecular Weight: 172.18
References & Citations: [1]Sano K, et al. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. Bioconjug Chem. 2013 May 15;24(5):811-6.
Shipping Conditions: Room Temperature
Storage Conditions: 4°C (Powder, stored under nitrogen)
Clinical Information: No Development Reported

Cat	Name
HY-118764-01	Propargyl-PEG2-acid
HY-118764-02	Propargyl-PEG2-acid
HY-140085	N-(PEG2-C2-acid)-N-bis(PEG2-propargyl)
HY-W051634-07	Propargyl-PEG2-amine
HY-W051634-04	Propargyl-PEG2-amine
HY-W051634-03	Propargyl-PEG2-amine
HY-W051634-01	Propargyl-PEG2-amine
HY-130584-03	Propargyl-PEG2-MS
HY-138740	Azido-PEG2-propargyl
HY-140083	Propargyl-PEG2-N-bis(PEG2)

Cat	Name
T16597-10mg	Propargyl-PEG2-acid
T16597-1g	Propargyl-PEG2-acid
T16597-50mg	Propargyl-PEG2-acid
B2014798	Propargyl-PEG2 Acid
T16597-5mg	Propargyl-PEG2-acid
BA2448-5000	Propargyl-PEG2-acid
571648	Propargyl-PEG2-acid
T16597-1mg	Propargyl-PEG2-acid
571768	N-(Acid-PEG2)-N-bis(PEG2-propargyl)
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