Propargyl-PEG2-amine
CAT:
804-HY-W051634-07
Size:
500 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Propargyl-PEG2-amine
- CAS Number: 944561-44-8
- UNSPSC Description: Propargyl-PEG2-amine is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG2-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1][2]. Propargyl-PEG2-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: ADC Linker; PROTAC Linkers
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/propargyl-peg2-amine.html
- Purity: 99.64
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: NCCOCCOCC#C
- Molecular Weight: 143.18
- References & Citations: [1]Changchun Wang, et al. A kind of antibody coupling matter and its construction method containing boron ester units polymer. CN108721642A.|[2]Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported